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A comparative study of single-dose treatment of chancroid using thiamphenicol versus Azithromycin BJID
B. Junior,Walter; Di Chiacchio,Nilton G.; Di Chiacchio,Nilton; Romiti,Ricardo; Criado,Paulo R.; Velho,Paulo Eduardo N. Ferreira.
A study was conducted in São Paulo, Brazil, to compare azithromycin with thiamphenicol for the single-dose treatment of chancroid. In all, 54 men with chancroid were tested. The etiology was determined by clinical characterization and direct bacterioscopy with Gram staining. None of the patients had positive serology or dark-field examination indicating active infection with Treponema pallidum. Genital infections due to Neisseria gonorrhoeae and herpes simplex virus were excluded by polymerase chain reaction testing. For 54 patients with chancroid, cure rates with single-dose treatment were 73% with azithromycin and 89% with thiamphenicol. HIV seropositivity was found to be associated with treatment failure (p=0.001). The treatment failed in all HIV...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Azithromycin; Chancroid; Haemophilus ducreyi; Single dose; Thiamphenicol.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000300012
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Donovanosis treated with thiamphenicol BJID
Belda Junior,Walter; Velho,Paulo Eduardo Neves Ferreira; Arnone,Marcelo; Romitti,Ricardo.
Ten patients with donovanosis were treated with thiamphenicol for two weeks. In eight of them, included two HIV infected patients, lesions healed. The safety profile of thiamphenicol makes it a useful and cost-effective agent in the management of donovanosis. Randomized controlled trials should be conducted with these treatment options.
Tipo: Info:eu-repo/semantics/other Palavras-chave: Azithromycin; Granuloma Inguinale; Sexually transmitted disease; Therapy; Thiamphenicol.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000400002
Registros recuperados: 2
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